40 Hz vibrations reduce Alzheimer’s pathology, symptoms in mouse models

Evidence that noninvasive sensory stimulation of 40 Hz gamma frequency brain rhythms can reduce Alzheimer’s disease pathology and symptoms, already shown with light and sound by multiple research groups in mice and humans, now extends to tactile stimulation. A new study by MIT scientists shows that Alzheimer’s model mice exposed to 40 Hz vibration for …

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Newly discovered bacterial communication system aids antimicrobial resistance

Researchers have discovered a new stress signaling system that enables bacteria cells to adapt and protect themselves against the immune system and certain antibiotics. An enzyme, RlmN, was observed to directly sense chemical and environmental stresses, and rapidly signal for the production of other proteins that allow the bacteria cell to adapt and survive. This …

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Making sense of cell fate

Despite the proliferation of novel therapies such as immunotherapy or targeted therapies, radiation and chemotherapy remain the frontline treatment for cancer patients. About half of all patients still receive radiation and 60-80 percent receive chemotherapy. Both radiation and chemotherapy work by damaging DNA, taking advantage of a vulnerability specific to cancer cells. Healthy cells are …

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Soft optical fibers block pain while moving and stretching with the body

Scientists have a new tool to precisely illuminate the roots of nerve pain. Engineers at MIT have developed soft and implantable fibers that can deliver light to major nerves through the body. When these nerves are genetically manipulated to respond to light, the fibers can send pulses of light to the nerves to inhibit pain. …

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Light-activated muscle grafts show promise in aiding muscle recovery post-trauma

Severe traumatic injuries that destroy large volumes of muscle can impact a person’s health, mobility, and quality of life for a lifetime. Promising new research co-led by Ritu Raman, the d’Arbeloff Career Development Assistant Professor of Mechanical Engineering, and MIT collaborators aims to restore mobility for those who have lost muscle through disease or trauma. “For …

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Celebrating Kendall Square’s past and shaping its future

Kendall Square’s community took a deep dive into the history and future of the region at the Kendall Square Association’s 15th annual meeting on Oct. 19. It’s no secret that Kendall Square, located in Cambridge, Massachusetts, moves fast. The event, titled “Looking Back, Looking Ahead,” gave community members a chance to pause and reflect on …

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Wobbly gel mat trains muscle cells to work together

There’s no doubt that exercise does a body good, including strengthening and toning our muscles. But how exactly does exercise make this happen? As we run and lift and stretch, our muscles experience chemical signals from surrounding cells, as well as mechanical forces from jostling against tissues. Some physiologists wonder: Is it the body’s natural …

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