Scientists have identified mutations in the CPD gene as a key cause of a rare congenital hearing loss, revealing how disruptions in arginine and nitric oxide signaling damage sensory cells in the ear. Using mouse and fruit fly models, the team showed that restoring arginine levels or using sildenafil improved cell survival and hearing function.
Scientists have identified mutations in the CPD gene as a key cause of a rare congenital hearing loss, revealing how disruptions in arginine and nitric oxide signaling damage sensory cells in the ear. Using mouse and fruit fly models, the team showed that restoring arginine levels or using sildenafil improved cell survival and hearing function. Scientists have identified mutations in the CPD gene as a key cause of a rare congenital hearing loss, revealing how disruptions in arginine and nitric oxide signaling damage sensory cells in the ear. Using mouse and fruit fly models, the team showed that restoring arginine levels or using sildenafil improved cell survival and hearing function.