Texas A&M researchers found that in an aggressive kidney cancer, RNA builds “droplet hubs” that activate tumor genes. By creating a molecular switch to dissolve these hubs, they stopped cancer growth in lab and mouse tests. The work reveals how RNA can be hijacked to fuel disease, and how breaking its scaffolding could lead to new therapies for multiple pediatric cancers.
Texas A&M researchers found that in an aggressive kidney cancer, RNA builds “droplet hubs” that activate tumor genes. By creating a molecular switch to dissolve these hubs, they stopped cancer growth in lab and mouse tests. The work reveals how RNA can be hijacked to fuel disease, and how breaking its scaffolding could lead to new therapies for multiple pediatric cancers. Texas A&M researchers found that in an aggressive kidney cancer, RNA builds “droplet hubs” that activate tumor genes. By creating a molecular switch to dissolve these hubs, they stopped cancer growth in lab and mouse tests. The work reveals how RNA can be hijacked to fuel disease, and how breaking its scaffolding could lead to new therapies for multiple pediatric cancers.