Hidden cellular “power switch” could transform Parkinson’s treatment

Researchers uncovered a key cellular regulator, PP2A-B55alpha, that controls both the cleanup of damaged mitochondria and the creation of new ones. In Parkinson’s disease models, reducing this regulator improved symptoms and mitochondrial health. The findings could inspire new drugs for Parkinson’s, mitochondrial disorders, and even cancer.

​Researchers uncovered a key cellular regulator, PP2A-B55alpha, that controls both the cleanup of damaged mitochondria and the creation of new ones. In Parkinson’s disease models, reducing this regulator improved symptoms and mitochondrial health. The findings could inspire new drugs for Parkinson’s, mitochondrial disorders, and even cancer. Researchers uncovered a key cellular regulator, PP2A-B55alpha, that controls both the cleanup of damaged mitochondria and the creation of new ones. In Parkinson’s disease models, reducing this regulator improved symptoms and mitochondrial health. The findings could inspire new drugs for Parkinson’s, mitochondrial disorders, and even cancer. 

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