When cancer cells feel squeezed, they become more dangerous

New research shows that cancer cells don’t just grow; they adapt when stressed. When squeezed inside tissues, they transform into more invasive, drug-resistant versions of themselves. A protein called HMGB2 helps flip this dangerous switch, giving the cells new powers to escape. The findings reveal how the tumor’s environment itself can drive cancer’s deadly flexibility.

​New research shows that cancer cells don’t just grow; they adapt when stressed. When squeezed inside tissues, they transform into more invasive, drug-resistant versions of themselves. A protein called HMGB2 helps flip this dangerous switch, giving the cells new powers to escape. The findings reveal how the tumor’s environment itself can drive cancer’s deadly flexibility. New research shows that cancer cells don’t just grow; they adapt when stressed. When squeezed inside tissues, they transform into more invasive, drug-resistant versions of themselves. A protein called HMGB2 helps flip this dangerous switch, giving the cells new powers to escape. The findings reveal how the tumor’s environment itself can drive cancer’s deadly flexibility. 

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