Chemists at the University of Geneva and University of Pisa have crafted a novel family of chiral molecules whose mirror-image “handedness” remains rock-solid for tens of thousands of years. By swapping the usual carbon-bound arms for oxygen and nitrogen, they introduced an unprecedented stereogenic center and proved its extreme resilience through dynamic chromatography and quantum calculations. This breakthrough not only prevents life-saving drugs from flipping into harmful twins but also unlocks fresh 3D architectures for future medicines and smart materials.
Chemists at the University of Geneva and University of Pisa have crafted a novel family of chiral molecules whose mirror-image “handedness” remains rock-solid for tens of thousands of years. By swapping the usual carbon-bound arms for oxygen and nitrogen, they introduced an unprecedented stereogenic center and proved its extreme resilience through dynamic chromatography and quantum calculations. This breakthrough not only prevents life-saving drugs from flipping into harmful twins but also unlocks fresh 3D architectures for future medicines and smart materials. Chemists at the University of Geneva and University of Pisa have crafted a novel family of chiral molecules whose mirror-image “handedness” remains rock-solid for tens of thousands of years. By swapping the usual carbon-bound arms for oxygen and nitrogen, they introduced an unprecedented stereogenic center and proved its extreme resilience through dynamic chromatography and quantum calculations. This breakthrough not only prevents life-saving drugs from flipping into harmful twins but also unlocks fresh 3D architectures for future medicines and smart materials.