‘Goldilocks’ binding strength determines anti-cancer T-cell efficacy and fate

Findings showed that how tight a parental T cell binds to a cancer-related protein determines whether its offspring will become functional anti-cancer effector cells or dysfunctional ‘exhausted’ T cells.

​Findings showed that how tight a parental T cell binds to a cancer-related protein determines whether its offspring will become functional anti-cancer effector cells or dysfunctional ‘exhausted’ T cells. Findings showed that how tight a parental T cell binds to a cancer-related protein determines whether its offspring will become functional anti-cancer effector cells or dysfunctional ‘exhausted’ T cells.