How immune cells communicate to fight viruses

Chemokines are signalling proteins that orchestrate the interaction of immune cells against pathogens and tumors. To understand this complex network, various techniques have been developed to identify chemokine-producing cells. However, it has not yet been possible to determine which cells react to these chemokines. Researchers have now developed a new class of genetically modified mice …

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Circadian rhythms can influence drugs’ effectiveness

Researchers discovered that more than 300 liver genes are under circadian control: Circadian variations affect how much of a drug is available and how effectively the body can break it down. ​Researchers discovered that more than 300 liver genes are under circadian control: Circadian variations affect how much of a drug is available and how …

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Maternal grandmothers’ support buffers children against the impacts of adversity

A study shows that investment by maternal grandmothers can improve the well-being of grandchildren who have faced adversities in life. The positive effects can last well into adulthood. ​A study shows that investment by maternal grandmothers can improve the well-being of grandchildren who have faced adversities in life. The positive effects can last well into …

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Treatment for deadly superbug C. diff may be weakening

The antibiotic vancomycin, recommended as first-line treatment for infection caused by the deadly superbug C. difficile (C. diff), may not be living up to its promise, according to new research. ​The antibiotic vancomycin, recommended as first-line treatment for infection caused by the deadly superbug C. difficile (C. diff), may not be living up to its …

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RNA modification is responsible for the disruption of mitochondrial protein synthesis in Alzheimer’s disease

A team of researchers has identified a mechanism that causes mitochondrial dysfunction in Alzheimer’s patients resulting in a reduction of the supply of energy to the brain. ​A team of researchers has identified a mechanism that causes mitochondrial dysfunction in Alzheimer’s patients resulting in a reduction of the supply of energy to the brain. A team …

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Advance in the treatment of acute heart failure identified

A multicenter study has identified a potential new treatment for acute heart failure, a leading cause of hospitalization and death. ​A multicenter study has identified a potential new treatment for acute heart failure, a leading cause of hospitalization and death. A multicenter study has identified a potential new treatment for acute heart failure, a leading cause …

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How Pluto got its heart

The mystery of how Pluto got a giant heart-shaped feature on its surface has finally been solved by an international team of astrophysicists. The team is the first to successfully reproduce the unusual shape with numerical simulations, attributing it to a giant and slow oblique-angle impact. ​The mystery of how Pluto got a giant heart-shaped …

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Simulated microgravity affects sleep and physiological rhythms

Simulated effects of microgravity significantly affect rhythmicity and sleep in humans, a new study finds. Such disturbances could negatively affect the physiology and performance of astronauts in space. ​Simulated effects of microgravity significantly affect rhythmicity and sleep in humans, a new study finds. Such disturbances could negatively affect the physiology and performance of astronauts in …

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More economical and sustainable rechargeable batteries

Lithium salts make batteries powerful but expensive. An ultralow-concentration electrolyte based on the lithium salt LiDFOB may be a more economical and more sustainable alternative. Cells using these electrolytes and conventional electrodes have been demonstrated to have high performance. In addition, the electrolyte could facilitate both production and recycling of the batteries. ​Lithium salts make …

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