mRNA technology could be possible treatment for rare diseases

By exploiting the technology used in Covid-19 vaccines, a team of scientists has created an effective therapy for a rare disease, in a study in mice, demonstrating the technology’s potential therapeutic use in people. ​By exploiting the technology used in Covid-19 vaccines, a team of scientists has created an effective therapy for a rare disease, …

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Genetics may influence the body’s response to low oxygen

Researchers uncovered a fundamental mechanism that controls the body’s response to limited oxygen and regulates blood vessel disease of the lung. ​Researchers uncovered a fundamental mechanism that controls the body’s response to limited oxygen and regulates blood vessel disease of the lung. Researchers uncovered a fundamental mechanism that controls the body’s response to limited oxygen and …

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Natural compounds derived from soy and other plants reduce breast cancer recurrence and improve survival

Soy compounds called isoflavones are among the plant-derived compounds that may significantly reduce the risk of breast cancer recurrence or death, according to a new meta-analysis. ​Soy compounds called isoflavones are among the plant-derived compounds that may significantly reduce the risk of breast cancer recurrence or death, according to a new meta-analysis. Soy compounds called isoflavones …

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Noninvasive technique reveals how cells’ gene expression changes over time

A new method can track changes in live cell gene expression over extended periods of time. Based on Raman spectroscopy, the method doesn’t harm cells and can be performed repeatedly. ​A new method can track changes in live cell gene expression over extended periods of time. Based on Raman spectroscopy, the method doesn’t harm cells …

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Exposure therapy addressing fear of spiders can also reduce fear of heights

Exposure therapy for a specific fear can also help reduce other fears. This is the conclusion reached by psychologists who studied 50 people with a fear of spiders and heights. Although they only treated the fear of spiders, the fear of heights was likewise reduced in the process. ​Exposure therapy for a specific fear can …

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Special brain cells react to unexpected situations

New research from the Netherlands Institute for Neuroscience shows that chandelier cells, a specific type of brain cell, become active during unexpected situations. ‘Researchers have been wondering about the functionality of these cells for a long time’. ​New research from the Netherlands Institute for Neuroscience shows that chandelier cells, a specific type of brain cell, …

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Traumatic stress associated with smaller brain region

Research reveals that adults with PTSD have a 2% smaller cerebellum than people without the disorder. The finding expands understanding of the cerebellum’s role in the brain beyond balance and movement to include emotion and cognition and also suggests that targeting the cerebellum may improve current treatments for PTSD, such as deep brain stimulation. ​Research …

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New research sheds light on an old fossil solving an evolutionary mystery

Picrodontids — an extinct family of placental mammals that lived several million years after the extinction of the dinosaurs — are not primates as previously believed. ​Picrodontids — an extinct family of placental mammals that lived several million years after the extinction of the dinosaurs — are not primates as previously believed. Picrodontids — an extinct …

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How ‘pioneers’ blaze the one trail that determines cell fate

A new CRISPR interference (CRISPRi) model explores how the pioneer transcription factor FOXA controls human endoderm differentiation during liver development, and how the pioneer transcription factor OCT4 influences the behavior of pluripotent stem cells. The unexpected findings could influence future organoid and cell reprogramming studies. ​A new CRISPR interference (CRISPRi) model explores how the pioneer …

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