Puffed-up MOFs for improved drug delivery

The spongelike structure of metal organic frameworks (MOFs) allows these polymers to possibly carry and deliver a range of therapeutic compounds. Now, researchers treated a chromium-containing MOF with a dose of acetic acid, more concentrated than in vinegar, to expand its pore size and surface area. The puffed-up MOFs held more ibuprofen or chemotherapy drug compared to the original version and had improved performance as a potential drug-delivery vehicle.

​The spongelike structure of metal organic frameworks (MOFs) allows these polymers to possibly carry and deliver a range of therapeutic compounds. Now, researchers treated a chromium-containing MOF with a dose of acetic acid, more concentrated than in vinegar, to expand its pore size and surface area. The puffed-up MOFs held more ibuprofen or chemotherapy drug compared to the original version and had improved performance as a potential drug-delivery vehicle. The spongelike structure of metal organic frameworks (MOFs) allows these polymers to possibly carry and deliver a range of therapeutic compounds. Now, researchers treated a chromium-containing MOF with a dose of acetic acid, more concentrated than in vinegar, to expand its pore size and surface area. The puffed-up MOFs held more ibuprofen or chemotherapy drug compared to the original version and had improved performance as a potential drug-delivery vehicle. 

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