Stinky, bitter, and painful: A novel insect repellent attacks multiple sensory pathways

Researchers found that a Transient Receptor Potential (TRP) A1 stimulant, 2-methylthiazoline (2MT), act as a potent insect repellent in Drosophila. 2MT induces aversive behaviors via olfactory, gustatory, and nociceptive sensory pathways. 2MT acts on TRPA1 through specific cysteine residues that are conserved across many insect pest species.

​Researchers found that a Transient Receptor Potential (TRP) A1 stimulant, 2-methylthiazoline (2MT), act as a potent insect repellent in Drosophila. 2MT induces aversive behaviors via olfactory, gustatory, and nociceptive sensory pathways. 2MT acts on TRPA1 through specific cysteine residues that are conserved across many insect pest species. Researchers found that a Transient Receptor Potential (TRP) A1 stimulant, 2-methylthiazoline (2MT), act as a potent insect repellent in Drosophila. 2MT induces aversive behaviors via olfactory, gustatory, and nociceptive sensory pathways. 2MT acts on TRPA1 through specific cysteine residues that are conserved across many insect pest species.