Researchers have been working to better understand what drives melanoma brain metastasis. They now report on the identification of a cell signaling pathway that regulates the metastatic spread of melanoma cells to the brain. Researchers have been working to better understand what drives melanoma brain metastasis. They now report on the identification of a cell …
Scientists have developed an injectable or catheter-administered hydrogel with enhanced capabilities for treating hepatocellular carcinoma, a deadly form of liver cancer. This drug-eluting hydrogel can provide sustained, pH-dependent drug co-delivery and has capabilities for promoting anti-tumor immune responses. This reduces tumor cell proliferation and growth and offers a more efficient means of enabling tumor cell …
Enhanced treatment of liver carcinoma with a drug-eluting hydrogel Read More »
The San Joaquin Valley in California has experienced vast variability in climate extremes, with droughts and floods that were more severe and lasted longer than what has been seen in the modern record, according to a new study of 600 years of tree rings from the valley. The San Joaquin Valley in California has experienced …
600 years of tree rings reveal climate risks in California Read More »
Newly discovered iron storage ‘ferrosomes’ inside the bacterium C. diff — the leading cause of hospital-acquired infections — are important for infection in an animal model and could offer new targets for antibacterial drugs. They also represent a rare demonstration of a membrane-bound structure inside a pathogenic bacterium, upsetting the biological dogma that bacteria do …
Novel C. diff structures are required for infection, offer new therapeutic targets Read More »
A new artificial intelligence computer program can generate doctors’ notes so well that two physicians couldn’t tell the difference, according to an early study from both groups. A new artificial intelligence computer program can generate doctors’ notes so well that two physicians couldn’t tell the difference, according to an early study from both groups. A new …
Optimal windows exist for action and perception during the 0.8 seconds of a heartbeat, according to new research. The sequence of contraction and relaxation is linked to changes in the motor system and its ability to respond to stimulation, and this could have implications for treatments for depression and stroke that excite nerve cells. Optimal …
Heart over head? Stages of the heart’s cycle affect neural responses Read More »
The largest review of papers for brain cancer that has spread from the lungs has found abnormalities in the brain cancer and for which licensed drugs could be clinically trialed to find out if they could treat the disease. The research also found genetic differences between smokers and non-smokers. The largest review of papers for …
Drugs already licensed could be trialled to potentially treat secondary brain cancer Read More »
Ancient animals were walking around on bird-like feet over 210 million years ago, according to a new study. Ancient animals were walking around on bird-like feet over 210 million years ago, according to a new study. Ancient animals were walking around on bird-like feet over 210 million years ago, according to a new study.
Many people take cannabis to help them sleep, but there is little evidence that the drug makes a difference Many people take cannabis to help them sleep, but there is little evidence that the drug makes a difference Many people take cannabis to help them sleep, but there is little evidence that the drug makes a …
Astronomers have used recent observations made with the James Webb Space Telescope to study the atmosphere of the nearby exoplanet WASP-107b. Peering deep into the fluffy atmosphere of WASP-107b they discovered not only water vapor and sulfur dioxide, but even silicate sand clouds. These particles reside within a dynamic atmosphere that exhibits vigorous transport of …